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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM81001
Substrate
n/a
Meas. Tech.
Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase
IC50
50000±n/a nM
Citation
 PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay (2011)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b
Type:
Enzyme
Mol. Mass.:
59258.58
Organism:
Homo sapiens (Human)
Description:
P11413
Residue:
515
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
  
Inhibitor
Name:
BDBM81001
Synonyms:
MLS000029793 | N-(5-Isopropyl-[1,3,4]thiadiazol-2-yl)-3-tetrazol-1-yl-benzamide | N-(5-isopropyl-1,3,4-thiadiazol-2-yl)-3-(tetrazol-1-yl)benzamide | N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-3-(1,2,3,4-tetrazol-1-yl)benzamide | N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-3-(1-tetrazolyl)benzamide | N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-3-(tetrazol-1-yl)benzamide | SMR000004219 | cid_652942
Type:
Small organic molecule
Emp. Form.:
C13H13N7OS
Mol. Mass.:
315.354
SMILES:
CC(C)c1nnc(NC(=O)c2cccc(c2)-n2cnnn2)s1
Structure:
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