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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM77737
Substrate
n/a
Meas. Tech.
Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase
IC50
>80000±n/a nM
Citation
 PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay (2011)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b
Type:
Enzyme
Mol. Mass.:
59258.58
Organism:
Homo sapiens (Human)
Description:
P11413
Residue:
515
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
  
Inhibitor
Name:
BDBM77737
Synonyms:
2,5-dimethyl-1-phenyl-N-(p-tolyl)pyrrole-3-carboxamide | 2,5-dimethyl-N-(4-methylphenyl)-1-phenyl-3-pyrrolecarboxamide | 2,5-dimethyl-N-(4-methylphenyl)-1-phenyl-pyrrole-3-carboxamide | 2,5-dimethyl-N-(4-methylphenyl)-1-phenylpyrrole-3-carboxamide | MLS000390701 | SMR000259739 | cid_2368804
Type:
Small organic molecule
Emp. Form.:
C20H20N2O
Mol. Mass.:
304.3856
SMILES:
Cc1cc(C(=O)Nc2ccc(C)cc2)c(C)n1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: