Reaction Details Report a problem with these data
Target
Alpha-1A adrenergic receptor
Ligand
BDBM29568
Substrate
n/a
Ki
0.33±n/a nM
Comments
PDSP_1528
Citation
 Lomasney, JW; Cotecchia, S; Lorenz, W; Leung, WY; Schwinn, DA; Yang-Feng, TL; Brownstein, M; Lefkowitz, RJ; Caron, MG Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. J Biol Chem 266:6365-9 (1991) [PubMed] 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
Alpha-1A adrenoreceptor | Alpha-1 adrenoreceptor | adrenergic Alpha1A | Alpha-1A adrenoceptor | Alpha-1C adrenergic receptor | ADA1A_RAT | Adra1a | Adra1c
Type:
Protein
Mol. Mass.:
51620.15
Organism:
Rat
Description:
P43140
Residue:
466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNVPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTLHPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACTTARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
  
Inhibitor
Name:
BDBM29568
Synonyms:
[3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCHLORIDE | PRAZOSIN | CHEMBL2 | [3H]-Pratsiol | [3H]-Prazosin
Type:
radiolabeled ligand
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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