Reaction Details
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Report a problem with these dataTarget
Norepinephrine transporter
Ligand
BDBM50026952
Substrate
n/a
Ki
5.4±n/a nM
Comments
PDSP_3887
Citation
Hyttel, J; Larsen, JJ Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of dopamine, noradrenaline, and serotonin. J Neurochem 44:1615-22 (1985) [PubMed] Article More Info.:
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
Inhibitor
Name:
BDBM50026952
Synonyms:
(cis) [3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine(LR 5182) | CHEMBL322067 | LR 5182 | [(2R,3S)-3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine
Type:
Small organic molecule
Emp. Form.:
C17H23Cl2N
Mol. Mass.:
312.277
SMILES:
CN(C)C[C@@H]1C2CCC(CC2)[C@@H]1c1ccc(Cl)c(Cl)c1 |wU:11.13,4.3,TLB:12:11:6.7:10.9,THB:3:4:6.7:10.9,(4.42,-5.07,;3.76,-3.67,;2.22,-3.53,;4.65,-2.41,;4,-1.01,;5.68,-.26,;5.79,1.35,;5.19,2.75,;5.16,1.21,;6.61,.69,;7.15,-.75,;3.76,.53,;2.43,1.3,;1.1,.53,;-.23,1.3,;-.23,2.84,;-1.58,3.63,;1.1,3.61,;1.1,5.15,;2.43,2.84,)|
Structure:
