Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50020965
Substrate
n/a
Ki
419±n/a nM
Comments
PDSP_2494
Citation
 Bruns, RF; Lu, GH; Pugsley, TA Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes. Mol Pharmacol 29:331-46 (1986) [PubMed] 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50020965
Synonyms:
8-(4-Methoxy-phenyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione | 8-(4-Methoxyphenyl)theophylline | 8-(4-methoxyphenyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione | CHEMBL11635
Type:
Small organic molecule
Emp. Form.:
C14H14N4O3
Mol. Mass.:
286.286
SMILES:
COc1ccc(cc1)-c1nc2n(C)c(=O)n(C)c(=O)c2[nH]1
Structure:
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