Reaction Details
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Report a problem with these dataTarget
Alpha-1B adrenergic receptor
Ligand
BDBM81444
Substrate
n/a
Ki
5.2±n/a nM
Comments
PDSP_1955
Citation
Horie, K; Hirasawa, A; Tsujimoto, G The pharmacological profile of cloned and stably expressed alpha 1b-adrenoceptor in CHO cells. Eur J Pharmacol 268:399-407 (1994) [PubMed] Article More Info.:
Target
Name:
Alpha-1B adrenergic receptor
Synonyms:
ADA1B_MESAU | ADRA1B | Adrenergic receptor alpha | Alpha-1b adrenergic receptor | adrenergic Alpha1B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56514.13
Organism:
C.H.O.
Description:
adrenergic Alpha1B ADRA1B C.H.O.::P18841
Residue:
515
Sequence:
MNPDLDTGHNTSAPAQWGELKDANFTGPNQTSSNSTLPQLDVTRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTVLPFSATLEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFMRILGCQCRSGRRRRRRRRLGACAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGSQRTLPSASPSPGYLGRGAQPPLELCAYPEWKSGALLSLPEPPGRRGRLDSGPLFTFKLLGEPESPGTEGDASNGGCDATTDLANGQPGFKSNMPLAPGHF
Inhibitor
Name:
BDBM81444
Synonyms:
CAS_185453 | NSC_185453 | WB 4101 | WB-4101
Type:
Small organic molecule
Emp. Form.:
C25H27NO5
Mol. Mass.:
421.4856
SMILES:
COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1
Structure:
