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Target
Alpha-2A adrenergic receptor
Ligand
BDBM50013515
Substrate
n/a
Ki
0.37±n/a nM
Comments
PDSP_1590
Citation
 O'Rourke, MF; Iversen, LJ; Lomasney, JW; Bylund, DB Species orthologs of the alpha-2A adrenergic receptor: the pharmacological properties of the bovine and rat receptors differ from the human and porcine receptors. J Pharmacol Exp Ther 271:735-40 (1994) [PubMed] 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
Alpha-2A adrenergic receptor | adrenergic Alpha2A | adrenergic Alpha2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48998.96
Organism:
Pig
Description:
adrenergic Alpha2 0 PIG::P18871
Residue:
450
Sequence:
MGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGGQQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAAALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSEHAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM50013515
Synonyms:
yohimbic acid methyl ester | 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester | CORYNANTHINE | Johimbin | Yohimbine | cid_8969 | (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester | Quebrachin | Yohimbin | YOHIMBINE CHLORIDE | CHEMBL15245 | (+)-yohimbine | aphrodine | corynine | quebrachine | RAUWOLSCINE | methyl 17alpha-hydroxyyohimban-16alpha-carboxylate
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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