Reaction Details
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Report a problem with these dataTarget
Transmembrane and immunoglobulin domain-containing 3
Ligand
BDBM50028567
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2586
Citation
van Galen, PJ; van Bergen, AH; Gallo-Rodriguez, C; Melman, N; Olah, ME; IJzerman, AP; Stiles, GL; Jacobson, KA A binding site model and structure-activity relationships for the rat A3 adenosine receptor. Mol Pharmacol 45:1101-11 (1994) [PubMed] More Info.:
Target
Name:
Transmembrane and immunoglobulin domain-containing 3
Synonyms:
ADENOSINE A3 | ADORA3 | Adora3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25707.75
Organism:
RAT
Description:
Q4V8H0
Residue:
232
Sequence:
MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPGTSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG
Inhibitor
Name:
BDBM50028567
Synonyms:
2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol | 5'-Deoxy-5'-aminoadenosine
Type:
Small organic molecule
Emp. Form.:
C10H14N6O3
Mol. Mass.:
266.2566
SMILES:
NCC1OC(C(O)C1O)n1cnc2c(N)ncnc12
Structure:
