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Target
Transmembrane and immunoglobulin domain-containing 3
Ligand
BDBM28422
Substrate
n/a
Ki
2470±n/a nM
Comments
PDSP_2559
Citation
 van Galen, PJ; van Bergen, AH; Gallo-Rodriguez, C; Melman, N; Olah, ME; IJzerman, AP; Stiles, GL; Jacobson, KA A binding site model and structure-activity relationships for the rat A3 adenosine receptor. Mol Pharmacol 45:1101-11 (1994) [PubMed] 
Target
Name:
Transmembrane and immunoglobulin domain-containing 3
Synonyms:
ADENOSINE A3 | ADORA3 | Adora3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25707.75
Organism:
RAT
Description:
Q4V8H0
Residue:
232
Sequence:
MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPGTSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG
  
Inhibitor
Name:
BDBM28422
Synonyms:
(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfanylium)butanoate | AdoMet | S-Adenosylmethionine | S-adenosyl-L-[carboxy-14C]methionine | [14COOH]AdoMet
Type:
radiolabeled substrate
Emp. Form.:
C15H22N6O5S
Mol. Mass.:
398.437
SMILES:
C[S+](CC[C@H](N)C([O-])=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Structure:
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