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Target
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Ligand
BDBM55549
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50
1988±104 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay (2011)[AID] 
Target
Name:
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:
CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29199.89
Organism:
Homo sapiens (Human)
Description:
gi_10864009
Residue:
261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
  
Inhibitor
Name:
BDBM55549
Synonyms:
2-hydroxy-N-[(Z)-[1-[2-(3-methylanilino)-2-oxoethyl]-2-oxo-3-indolylidene]amino]benzamide | 2-hydroxy-N-[(Z)-[1-[2-(3-methylanilino)-2-oxoethyl]-2-oxoindol-3-ylidene]amino]benzamide | 2-hydroxy-N-[(Z)-[2-keto-1-[2-keto-2-(m-toluidino)ethyl]indolin-3-ylidene]amino]benzamide | 2-{3-[(2-Hydroxy-benzoyl)-hydrazono]-2-oxo-2,3-dihydro-indol-1-yl}-N-m-tolyl-acetamide | MLS000548432 | N-[(Z)-[1-[2-[(3-methylphenyl)amino]-2-oxidanylidene-ethyl]-2-oxidanylidene-indol-3-ylidene]amino]-2-oxidanyl-benzamide | SMR000171366 | cid_6870326
Type:
Small organic molecule
Emp. Form.:
C24H20N4O4
Mol. Mass.:
428.44
SMILES:
Cc1cccc(NC(=O)CN2C(=O)\C(=N/NC(=O)c3ccccc3O)c3ccccc23)c1
Structure:
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