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Target
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Ligand
BDBM83150
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50
14580±453 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay (2011)[AID] 
Target
Name:
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:
CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29199.89
Organism:
Homo sapiens (Human)
Description:
gi_10864009
Residue:
261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
  
Inhibitor
Name:
BDBM83150
Synonyms:
6-(4-mesylphenyl)-N-morpholino-thieno[2,3-f][1,3]benzodioxole-7-carboxamide | 6-(4-methylsulfonylphenyl)-N-(4-morpholinyl)-7-thieno[2,3-f][1,3]benzodioxolecarboxamide | 6-(4-methylsulfonylphenyl)-N-morpholin-4-yl-thieno[2,3-f][1,3]benzodioxole-7-carboxamide | 6-(4-methylsulfonylphenyl)-N-morpholin-4-ylthieno[2,3-f][1,3]benzodioxole-7-carboxamide | MLS002473584 | SMR001397751 | cid_44202232
Type:
Small organic molecule
Emp. Form.:
C21H20N2O6S2
Mol. Mass.:
460.523
SMILES:
CS(=O)(=O)c1ccc(cc1)-c1sc2cc3OCOc3cc2c1C(=O)NN1CCOCC1
Structure:
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