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Target
Beta-lactamase
Ligand
BDBM83214
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
IC50
4385±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM83214
Synonyms:
(2Z,6E)-4-methyl-2,6-bis[(1-methyl-2-pyrrolyl)methylidene]-1-cyclohexanone | (2Z,6E)-4-methyl-2,6-bis[(1-methylpyrrol-2-yl)methylene]cyclohexanone | (2Z,6E)-4-methyl-2,6-bis[(1-methylpyrrol-2-yl)methylidene]cyclohexan-1-one | MLS000519844 | SMR000130262 | cid_6371672
Type:
Small organic molecule
Emp. Form.:
C19H22N2O
Mol. Mass.:
294.3908
SMILES:
CC1C\C(=C\c2cccn2C)C(=O)\C(C1)=C\c1cccn1C
Structure:
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