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Target
Beta-lactamase
Ligand
BDBM83270
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
IC50
4504±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM83270
Synonyms:
MLS002608484 | N-[[4-(diethylamino)phenyl]methylideneamino]-5-nitro-2-pyridinamine | N-[[4-(diethylamino)phenyl]methylideneamino]-5-nitro-pyridin-2-amine | N-[[4-(diethylamino)phenyl]methylideneamino]-5-nitropyridin-2-amine | SMR001527232 | cid_95917 | diethyl-[4-[[(5-nitro-2-pyridyl)hydrazono]methyl]phenyl]amine
Type:
Small organic molecule
Emp. Form.:
C16H19N5O2
Mol. Mass.:
313.3544
SMILES:
CCN(CC)c1ccc(CN=Nc2ccc(cn2)[N+]([O-])=O)cc1 |w:10.9|
Structure:
Search PDB for entries with ligand similarity: