Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM80864
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
2830±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM80864
Synonyms:
(3,4-dihydro-2H-naphthalen-1-ylideneamino) 4-methylbenzoate | 1-{[(4-methylbenzoyl)oxy]imino}-1,2,3,4-tetrahydronaphthalene | 4-methylbenzoic acid (3,4-dihydro-2H-naphthalen-1-ylideneamino) ester | 4-methylbenzoic acid (tetralin-1-ylideneamino) ester | MLS000546835 | SMR000180033 | cid_2766061
Type:
Small organic molecule
Emp. Form.:
C18H17NO2
Mol. Mass.:
279.3331
SMILES:
Cc1ccc(cc1)C(=O)ON=C1CCCc2ccccc12
Structure:
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