Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM58417
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
2260±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM58417
Synonyms:
2-[4-[3-(1,3-benzodioxol-5-yl)-5-(3-thienyl)isoxazol-4-yl]phenyl]cinchoninic acid | 2-[4-[3-(1,3-benzodioxol-5-yl)-5-(3-thiophenyl)-4-isoxazolyl]phenyl]-4-quinolinecarboxylic acid | 2-[4-[3-(1,3-benzodioxol-5-yl)-5-thiophen-3-yl-1,2-oxazol-4-yl]phenyl]quinoline-4-carboxylic acid | MLS001143167 | SMR000631649 | cid_24761252
Type:
Small organic molecule
Emp. Form.:
C30H18N2O5S
Mol. Mass.:
518.539
SMILES:
OC(=O)c1cc(nc2ccccc12)-c1ccc(cc1)-c1c(noc1-c1ccsc1)-c1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: