Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM51101
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM51101
Synonyms:
(benzalamino)-benzo[cd]indol-2-yl-amine | MLS000392783 | N-(benzylideneamino)benzo[cd]indol-2-amine | N-[(phenylmethylene)amino]-2-benzo[cd]indolamine | N-[(phenylmethylidene)amino]benzo[cd]indol-2-amine | SMR000261715 | [(E)-benzalamino]-benzo[cd]indol-2-yl-amine | cid_2315076
Type:
Small organic molecule
Emp. Form.:
C18H13N3
Mol. Mass.:
271.3159
SMILES:
N(N=Cc1ccccc1)C1=Nc2cccc3cccc1c23 |w:1.0,t:10|
Structure:
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