Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM77549
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM77549
Synonyms:
5-nitro-N-(2-pyrimidinyl)-2-furancarboxamide | 5-nitro-N-(2-pyrimidyl)-2-furamide | 5-nitro-N-pyrimidin-2-yl-furan-2-carboxamide | 5-nitro-N-pyrimidin-2-ylfuran-2-carboxamide | MLS000766077 | SMR000279783 | cid_771978
Type:
Small organic molecule
Emp. Form.:
C9H6N4O4
Mol. Mass.:
234.1683
SMILES:
[O-][N+](=O)c1ccc(o1)C(=O)Nc1ncccn1
Structure:
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