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Target
Sentrin-specific protease 8
Ligand
BDBM84060
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84060
Synonyms:
1-(1H-indol-3-yl)-2-(3-keto-2,4-dihydroquinoxalin-1-yl)ethane-1,2-dione | 1-(1H-indol-3-yl)-2-(3-oxidanylidene-2,4-dihydroquinoxalin-1-yl)ethane-1,2-dione | 1-(1H-indol-3-yl)-2-(3-oxo-2,4-dihydroquinoxalin-1-yl)ethane-1,2-dione | MLS-0454613.0002 | cid_5296023
Type:
Small organic molecule
Emp. Form.:
C18H13N3O3
Mol. Mass.:
319.3141
SMILES:
O=C(N1CC(=O)Nc2ccccc12)C(=O)c1c[nH]c2ccccc12
Structure:
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