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Target
Sentrin-specific protease 8
Ligand
BDBM84091
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84091
Synonyms:
(Z)-3-(3-hydroxy-4-methoxy-phenyl)-2-[3-(o-tolyl)-1,2,4-oxadiazol-5-yl]acrylonitrile | (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]-2-propenenitrile | (Z)-3-(3-hydroxy-4-methoxyphenyl)-2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]prop-2-enenitrile | (Z)-3-(4-methoxy-3-oxidanyl-phenyl)-2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]prop-2-enenitrile | MLS-0454629.0002 | cid_50898014
Type:
Small organic molecule
Emp. Form.:
C19H15N3O3
Mol. Mass.:
333.3407
SMILES:
COc1ccc(\C=C(\C#N)c2nc(no2)-c2ccccc2C)cc1O
Structure:
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