Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM68368
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
2440±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM68368
Synonyms:
MLS000027475 | N-(6-Ethoxy-benzothiazol-2-yl)-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)-acetamide | N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-(3-methylimidazo[4,5-b]pyridin-2-yl)sulfanyl-ethanamide | N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-(3-methylimidazo[4,5-b]pyridin-2-yl)sulfanylacetamide | N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[(3-methyl-2-imidazo[4,5-b]pyridinyl)thio]acetamide | N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[(3-methylimidazo[4,5-b]pyridin-2-yl)thio]acetamide | SMR000005801 | cid_652434
Type:
Small organic molecule
Emp. Form.:
C18H17N5O2S2
Mol. Mass.:
399.49
SMILES:
CCOc1ccc2nc(NC(=O)CSc3nc4cccnc4n3C)sc2c1
Structure:
Search PDB for entries with ligand similarity: