Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM84237
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
4820±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84237
Synonyms:
4-[2-phenyl-6-(p-tolylthio)pyrimidin-4-yl]morpholine | 4-[6-(4-methylphenyl)sulfanyl-2-phenyl-pyrimidin-4-yl]morpholine | 4-[6-(4-methylphenyl)sulfanyl-2-phenylpyrimidin-4-yl]morpholine | 4-[6-[(4-methylphenyl)thio]-2-phenyl-4-pyrimidinyl]morpholine | 4-{6-[(4-methylphenyl)sulfanyl]-2-phenyl-4-pyrimidinyl}morpholine | MLS000326647 | SMR000179171 | cid_1484653
Type:
Small organic molecule
Emp. Form.:
C21H21N3OS
Mol. Mass.:
363.476
SMILES:
Cc1ccc(Sc2cc(nc(n2)-c2ccccc2)N2CCOCC2)cc1
Structure:
Search PDB for entries with ligand similarity: