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Target
Beta-2 adrenergic receptor
Ligand
BDBM74832
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
52500±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM74832
Synonyms:
2-amino-4-phenyl-5,6-dihydro-4H-benzo[h][1]benzopyran-3-carbonitrile | 2-amino-4-phenyl-5,6-dihydro-4H-benzo[h]chromene-3-carbonitrile | 2-azanyl-4-phenyl-5,6-dihydro-4H-benzo[h]chromene-3-carbonitrile | MLS000569088 | SMR000172465 | cid_3166945
Type:
Small organic molecule
Emp. Form.:
C20H16N2O
Mol. Mass.:
300.3538
SMILES:
N=C1OC2=C(CCc3ccccc23)C(C1C#N)c1ccccc1 |t:3|
Structure:
Search PDB for entries with ligand similarity: