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Target
5-hydroxytryptamine receptor 6
Ligand
BDBM21393
Substrate
n/a
Ki
251.18±n/a nM
Comments
PDSP_205
Citation
 Plassat, JL; Amlaiky, N; Hen, R Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol Pharmacol 44:229-36 (1993) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_MOUSE | Htr6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47012.98
Organism:
MOUSE
Description:
5-HT6 HTR6 MOUSE::Q9R1C8
Residue:
440
Sequence:
MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTSAPGQCRLLASLPYVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTATAGQALETLQVPRTPRPGMESADSRRLTTKHSRKALKASLTLGILLSMFFVTWLPFFVASIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFVPCVHCPPEHRASPASPSMWTSHSGARPGLSLQQVLPLPLPPNSDSDSASGGTSGLQLTAQLLLPGEATRDPPPPTRAPTVVNFFVTDSVEPEIRQHPLGSPMN
  
Inhibitor
Name:
BDBM21393
Synonyms:
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-OH-DPAT | 8-OH-DPAT,(+) | 8-OH-DPAT,(-) | 8-hydroxy-N,N-dipropylaminotetralin | CHEMBL1788118 | CHEMBL505765 | CHEMBL56 | DPAT | US10562853, Compound 8-OH-DPAT | [3H]-8-OH-DPAT | cid_1220
Type:
radiolabeled ligand
Emp. Form.:
C16H25NO
Mol. Mass.:
247.3758
SMILES:
CCCN(CCC)C1CCc2cccc(O)c2C1
Structure:
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