Reaction Details Report a problem with these data
Target
ELAV-like protein 1
Ligand
BDBM94953
Substrate
n/a
Meas. Tech.
ChEMBL_1668505 (CHEMBL4018393)
IC50
44400±n/a nM
Citation
 Nasti, R; Rossi, D; Amadio, M; Pascale, A; Unver, MY; Hirsch, AKH; Collina, S Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs. J Med Chem 60:8257-8267 (2017) [PubMed]  Article 
Target
Name:
ELAV-like protein 1
Synonyms:
ELAV1_HUMAN | ELAVL1 | HUR | Hu-antigen R
Type:
PROTEIN
Mol. Mass.:
36102.56
Organism:
Homo sapiens (Human)
Description:
ChEMBL_654855
Residue:
326
Sequence:
MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK
  
Inhibitor
Name:
BDBM94953
Synonyms:
5-Amino-2-p-toluidinobenzenesulfonic acid | 5-amino-2-(4-methylanilino)benzenesulfonic acid | 5-amino-2-(p-toluidino)besylic acid | 5-azanyl-2-[(4-methylphenyl)amino]benzenesulfonic acid | MLS000736579 | SMR000528071 | cid_66672
Type:
Small organic molecule
Emp. Form.:
C13H14N2O3S
Mol. Mass.:
278.327
SMILES:
Cc1ccc(Nc2ccc(N)cc2S(O)(=O)=O)cc1
Structure:
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