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Target
ELAV-like protein 3
Ligand
BDBM50240690
Substrate
n/a
Meas. Tech.
ChEMBL_1668499 (CHEMBL4018387)
IC50
200±n/a nM
Citation
 Nasti, R; Rossi, D; Amadio, M; Pascale, A; Unver, MY; Hirsch, AKH; Collina, S Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs. J Med Chem 60:8257-8267 (2017) [PubMed]  Article 
Target
Name:
ELAV-like protein 3
Synonyms:
ELAV-like protein 3 | ELAV3_HUMAN | ELAVL3 | HUC | Hu-antigen C | PLE21 | Paraneoplastic cerebellar degeneration-associated antigen | Paraneoplastic limbic encephalitis antigen 21
Type:
PROTEIN
Mol. Mass.:
39557.78
Organism:
Homo sapiens
Description:
ChEMBL_117529
Residue:
367
Sequence:
MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA
  
Inhibitor
Name:
BDBM50240690
Synonyms:
CHEMBL4088244
Type:
Small organic molecule
Emp. Form.:
C23H20O11
Mol. Mass.:
472.3983
SMILES:
COc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1 |r|
Structure:
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