Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50253642
Substrate
n/a
Meas. Tech.
ChEBML_1685753
Ki
174±n/a nM
Citation
 Partyka, A; Kurczab, R; Canale, V; Sata?a, G; Marciniec, K; Pasierb, A; Jastrz?bska-Wi?sek, M; Paw?owski, M; Weso?owska, A; Bojarski, AJ; Zajdel, P The impact of the halogen bonding on D Bioorg Med Chem 25:3638-3648 (2017) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50253642
Synonyms:
CHEMBL4075422
Type:
Small organic molecule
Emp. Form.:
C26H32N4O2S
Mol. Mass.:
464.623
SMILES:
O=S(=O)(N1CCC(CCN2CCN(CC2)c2ccccc2)CC1)c1cncc2ccccc12
Structure:
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