Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50254664
Substrate
n/a
Meas. Tech.
ChEBML_1686375
EC50
53±n/a nM
Citation
 Qian, HY; Wang, ZL; Pan, YL; Chen, LL; Xie, X; Chen, JZ Development of Quinazoline/Pyrimidine-2,4(1 ACS Med Chem Lett 8:678-681 (2017) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50254664
Synonyms:
CHEMBL4089773
Type:
Small organic molecule
Emp. Form.:
C19H26ClN3O3
Mol. Mass.:
379.881
SMILES:
CCCCCn1c2c(Cl)cccc2c(=O)n(CC(=O)NC(C)(C)C)c1=O
Structure:
Search PDB for entries with ligand similarity: