Reaction Details Report a problem with these data
Target
CD209 antigen
Ligand
BDBM50260173
Substrate
n/a
Meas. Tech.
ChEBML_1692781
IC50
720000±n/a nM
Citation
 Tamburrini, A; Achilli, S; Vasile, F; Sattin, S; Vivès, C; Colombo, C; Fieschi, F; Bernardi, A Facile access to pseudo-thio-1,2-dimannoside, a new glycomimetic DC-SIGN antagonist. Bioorg Med Chem 25:5142-5147 (2017) [PubMed]  Article 
Target
Name:
CD209 antigen
Synonyms:
C-type lectin domain family 4 member L | CD209 | CD209_HUMAN | CD_antigen=CD209 | CLEC4L | DC-SIGN | DC-SIGN1 | Dendritic cell-specific ICAM-3-grabbing non-integrin 1
Type:
PROTEIN
Mol. Mass.:
45768.84
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104194
Residue:
404
Sequence:
MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA
  
Inhibitor
Name:
BDBM50260173
Synonyms:
CHEMBL4095576
Type:
Small organic molecule
Emp. Form.:
C17H28O11
Mol. Mass.:
408.3976
SMILES:
[H][C@@]1(C[C@@H]([C@H](C[C@@H]1OC)C(=O)OC)C(=O)OC)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: