Reaction Details Report a problem with these data
Target
Neuromedin-U receptor 2
Ligand
BDBM50049425
Substrate
n/a
Meas. Tech.
ChEBML_1696566
EC50
0.430000±n/a nM
Citation
 Nishizawa, N; Kanematsu-Yamaki, Y; Funata, M; Nagai, H; Shimizu, A; Fujita, H; Sakamoto, J; Takekawa, S; Asami, T A potent neuromedin U receptor 2-selective alkylated peptide. Bioorg Med Chem Lett 27:4626-4629 (2017) [PubMed]  Article 
Target
Name:
Neuromedin-U receptor 2
Synonyms:
NMU-R2 | NMUR2_MOUSE | Neuromedin-U receptor 2 | Nmur2
Type:
PROTEIN
Mol. Mass.:
44839.20
Organism:
Mus musculus
Description:
ChEMBL_109541
Residue:
395
Sequence:
MGKLENASWIHDSLMKYLNSTEEYLAYLCGPKRSDLSLPVSVVYALIFVVGVIGNLLVCLVIARHQTLKTPTNYYLFSLAVSDLLVLLLGMPLEVYELWHNYPFLFGPVGCYFKTALFETVCFASILSVTTVSIERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQQFPNGSSVPGSATCTVTKPIWVYNFIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEADKVTVNIHRPSRKSVTKMLFVLVLVFAICWTPFHVDRLFFSFVDEWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYNLLSRRFRAAFRNVVSPSCKWCHPQHRPQGPPAQKVIFLTECHLVELTEDAGPQFPCQSSIHNTQLTTVPCVEEVP
  
Inhibitor
Name:
BDBM50049425
Synonyms:
CHEMBL3356083
Type:
Small organic molecule
Emp. Form.:
C54H78N16O10
Mol. Mass.:
1111.2983
SMILES:
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O |r|
Structure:
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