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Target
Serine/threonine-protein kinase pim-2
Ligand
BDBM50261809
Substrate
n/a
Meas. Tech.
ChEBML_1696796
IC50
>30000±n/a nM
Citation
 Barberis, C; Moorcroft, N; Arendt, C; Levit, M; Moreno-Mazza, S; Batchelor, J; Mechin, I; Majid, T Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I. Bioorg Med Chem Lett 27:4730-4734 (2017) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase pim-2
Synonyms:
PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2)
Type:
Serine/threonine-protein kinase
Mol. Mass.:
34185.93
Organism:
Homo sapiens (Human)
Description:
Q9P1W9
Residue:
311
Sequence:
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
  
Inhibitor
Name:
BDBM50261809
Synonyms:
CHEMBL4098659
Type:
Small organic molecule
Emp. Form.:
C20H22ClN5O
Mol. Mass.:
383.875
SMILES:
CN1CCN(CC1)c1ccc(cc1)-c1cc2c(Cl)cc(nc2n1C)C(N)=O
Structure:
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