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Target
Peptidyl-prolyl cis-trans isomerase FKBP2
Ligand
BDBM50263407
Substrate
n/a
Meas. Tech.
ChEBML_1697926
Ki
61±n/a nM
Citation
 Pomplun, S; Sippel, C; Hähle, A; Tay, D; Shima, K; Klages, A; Ünal, CM; Rieß, B; Toh, HT; Hansen, G; Yoon, HS; Bracher, A; Preiser, P; Rupp, J; Steinert, M; Hausch, F Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins. J Med Chem 61:3660-3673 (2018) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase FKBP2
Synonyms:
13 kDa FK506-binding protein | 13 kDa FKBP | 5.2.1.8 | FK506-binding protein 2 | FKBP-13 | FKBP-2 | FKBP13 | FKBP2 | FKBP2_HUMAN | Immunophilin FKBP13 | PPIase FKBP2 | Peptidyl-prolyl cis-trans isomerase FKBP2 | Rotamase
Type:
PROTEIN
Mol. Mass.:
15655.64
Organism:
Homo sapiens
Description:
ChEMBL_117554
Residue:
142
Sequence:
MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRTEL
  
Inhibitor
Name:
BDBM50263407
Synonyms:
CHEMBL4090599
Type:
Small organic molecule
Emp. Form.:
C22H25Cl2N3O4S
Mol. Mass.:
498.423
SMILES:
[H][C@]12CCC[C@]([H])(N1S(=O)(=O)c1cc(Cl)cc(Cl)c1)C(=O)N(Cc1ccccn1)C[C@@H]2COC |r,TLB:31:30:7:2.3.4,20:19:7:2.3.4,THB:22:21:7:2.3.4|
Structure:
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