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Target
Cathepsin G
Ligand
BDBM50266994
Substrate
n/a
Meas. Tech.
ChEMBL_1701757 (CHEMBL4052990)
Ki
530±n/a nM
Citation
 Swedberg, JE; Li, CY; de Veer, SJ; Wang, CK; Craik, DJ Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold. J Med Chem 60:658-667 (2017) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50266994
Synonyms:
CHEMBL4103492
Type:
Small organic molecule
Emp. Form.:
C23H34N4O7
Mol. Mass.:
478.5387
SMILES:
CCCCC(NC(=O)[C@@H](NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C=O |r|
Structure:
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