Reaction Details Report a problem with these data
Target
Tyrosinase
Ligand
BDBM50441626
Substrate
n/a
Meas. Tech.
ChEMBL_1702181 (CHEMBL4053414)
IC50
90±n/a nM
Citation
 Li, K; Ji, S; Song, W; Kuang, Y; Lin, Y; Tang, S; Cui, Z; Qiao, X; Yu, S; Ye, M Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. J Nat Prod 80:334-346 (2017) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB
Type:
Protein
Mol. Mass.:
60388.08
Organism:
Homo sapiens (Human)
Description:
P14679
Residue:
529
Sequence:
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
  
Inhibitor
Name:
BDBM50441626
Synonyms:
GLABRIDIN | US9783551, Compound 1
Type:
Small organic molecule
Emp. Form.:
C20H20O4
Mol. Mass.:
324.3704
SMILES:
CC1(C)Oc2ccc3C[C@@H](COc3c2C=C1)c1ccc(O)cc1O |r,c:16|
Structure:
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