Reaction Details Report a problem with these data
Target
High mobility group protein B1
Ligand
BDBM26193
Substrate
n/a
Meas. Tech.
ChEMBL_1710853 (CHEMBL4120902)
Kd
1000±n/a nM
Citation
 VanPatten, S; Al-Abed, Y High Mobility Group Box-1 (HMGb1): Current Wisdom and Advancement as a Potential Drug Target. J Med Chem 61:5093-5107 (2018) [PubMed]  Article 
Target
Name:
High mobility group protein B1
Synonyms:
HMG-1 | HMG1 | HMGB1 | HMGB1_HUMAN | High mobility group protein 1
Type:
PROTEIN
Mol. Mass.:
24889.95
Organism:
Homo sapiens (Human)
Description:
ChEMBL_936211
Residue:
215
Sequence:
MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE
  
Inhibitor
Name:
BDBM26193
Synonyms:
2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHEMBL424 | phenol derivative, 7 | salicylic acid
Type:
Small organic molecule
Emp. Form.:
C7H6O3
Mol. Mass.:
138.1207
SMILES:
OC(=O)c1ccccc1O
Structure:
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