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Target
Casein kinase 1, delta tv1
Ligand
BDBM50256734
Substrate
n/a
Meas. Tech.
ChEMBL_1714298 (CHEMBL4124347)
IC50
>10000±n/a nM
Citation
 Dao, VH; Ourliac-Garnier, I; Bazin, MA; Jacquot, C; Baratte, B; Ruchaud, S; Bach, S; Grovel, O; Le Pape, P; Marchand, P Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration. Bioorg Med Chem Lett 28:2250-2255 (2018) [PubMed]  Article 
Target
Name:
Casein kinase 1, delta tv1
Synonyms:
CSNK1D
Type:
PROTEIN
Mol. Mass.:
47258.61
Organism:
Sus scrofa
Description:
ChEMBL_106594
Residue:
415
Sequence:
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEAAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIAGRVAASGLQSAVHR
  
Inhibitor
Name:
BDBM50256734
Synonyms:
(-)-Cercosporamide | CHEMBL475816
Type:
Small organic molecule
Emp. Form.:
C16H13NO7
Mol. Mass.:
331.2769
SMILES:
CC(=O)C1C(=O)C=C2Oc3c(c(O)cc(O)c3C(N)=O)[C@]2(C)C1=O |r,t:6|
Structure:
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