Reaction Details Report a problem with these data
Target
Oxoeicosanoid receptor 1
Ligand
BDBM50275215
Substrate
n/a
Meas. Tech.
ChEMBL_1714532 (CHEMBL4124581)
EC50
>100000±n/a nM
Citation
 Stepniewski, TM; Torrens-Fontanals, M; Rodríguez-Espigares, I; Giorgino, T; Primdahl, KG; Vik, A; Stenstrřm, Y; Selent, J; Hansen, TV Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorg Med Chem 26:3580-3587 (2018) [PubMed]  Article 
Target
Name:
Oxoeicosanoid receptor 1
Synonyms:
5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45833.20
Organism:
Homo sapiens (Human)
Description:
TG 1019 0 HUMAN::Q8TDS5
Residue:
423
Sequence:
MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
  
Inhibitor
Name:
BDBM50275215
Synonyms:
CHEMBL4128585
Type:
Small organic molecule
Emp. Form.:
C22H30O3
Mol. Mass.:
342.4718
SMILES:
CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C=C/C(=O)CCC(O)=O
Structure:
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