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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50029816
Substrate
n/a
Meas. Tech.
ChEMBL_1715376 (CHEMBL4125425)
IC50
37±n/a nM
Citation
 Baek, SC; Ryu, HW; Kang, MG; Lee, H; Park, D; Cho, ML; Oh, SR; Kim, H Selective inhibition of monoamine oxidase A by chelerythrine, an isoquinoline alkaloid. Bioorg Med Chem Lett 28:2403-2407 (2018) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
MAO-B | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) | AOFB_HUMAN | MAOB
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Human
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50029816
Synonyms:
Ro-19-6327 | 5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl)-amide | Lazabemide | CHEMBL279390
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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