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Target
Dipeptidyl peptidase 9
Ligand
BDBM11464
Substrate
n/a
Meas. Tech.
ChEBML_1717761
IC50
6600±n/a nM
Citation
 Rea, D; Van Elzen, R; De Winter, H; Van Goethem, S; Landuyt, B; Luyten, W; Schoofs, L; Van Der Veken, P; Augustyns, K; De Meester, I; Fülöp, V; Lambeir, AM Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling. Eur J Med Chem 139:482-491 (2017) [PubMed]  Article 
Target
Name:
Dipeptidyl peptidase 9
Synonyms:
DPP9 | Dipeptidyl peptidase 9
Type:
PROTEIN
Mol. Mass.:
102745.04
Organism:
Bos taurus
Description:
ChEMBL_117783
Residue:
902
Sequence:
MRKVKKLRLDNVNTGHWRSFSLNSQGAERMATGALTSERGDAAETEDPASRFQVQKHSWEGLRSIIHGSRKNSGLVVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPRKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHKGLSSVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGCKTLRILYEEVDESEVEIIHVPSPALEERKTDSYRYPRTGSKNPRIALKLAEFQTDSQGKIVSTQEKELVQPFSLLFPKVEYLARAGWTQDGKYAWAMFLDRPQQRLQLVLLPPALFIPTTDNEEQRAAFARAVPRDVQPYVVYEEVTDVWINVHDIFYPFPQAEGVDELCFIRANECKTGFCHLYKVTAVLRPRGYDWTQPFSPGDDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEVAGEIVRLTTPGFSHSCSMSQNFDMFISHYSSVGTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHAVQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQLGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGKKEKQKQEAGVQSEKKTHIHTPTPLE
  
Inhibitor
Name:
BDBM11464
Synonyms:
(2S,3S)-2-amino-3-methyl-1-(1,3-thiazolidin-3-yl)pentan-1-one | BMCL15687 Compound 4 | CHEMBL98408 | P32-98 | thiazolidide 2
Type:
Small organic molecule
Emp. Form.:
C9H18N2OS
Mol. Mass.:
202.317
SMILES:
CC[C@H](C)[C@H](N)C(=O)N1CCSC1 |r|
Structure:
Search PDB for entries with ligand similarity: