Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50284267
Substrate
n/a
Meas. Tech.
ChEMBL_1727013 (CHEMBL4142291)
Ki
786±n/a nM
Citation
 Hasan, M; Genovese, S; Fiorito, S; Epifano, F; Witt-Enderby, PA Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration. J Nat Prod 80:3324-3329 (2017) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50284267
Synonyms:
Boropinal
Type:
Small organic molecule
Emp. Form.:
C15H18O3
Mol. Mass.:
246.3016
SMILES:
[#6]-[#8]-c1cc(\[#6]=[#6]\[#6]=O)ccc1-[#8]-[#6]\[#6]=[#6](\[#6])-[#6]
Structure:
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