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Target
Cannabinoid receptor 2
Ligand
BDBM50286066
Substrate
n/a
Meas. Tech.
ChEMBL_1728853 (CHEMBL4144131)
EC50
21±n/a nM
Citation
 Han, S; Thoresen, L; Jung, JK; Zhu, X; Thatte, J; Solomon, M; Gaidarov, I; Unett, DJ; Yoon, WH; Barden, J; Sadeque, A; Usmani, A; Chen, C; Semple, G; Grottick, AJ; Al-Shamma, H; Christopher, R; Jones, RM Discovery of APD371: Identification of a Highly Potent and Selective CB ACS Med Chem Lett 8:1309-1313 (2017) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50286066
Synonyms:
CHEMBL4162987
Type:
Small organic molecule
Emp. Form.:
C18H23N5O2
Mol. Mass.:
341.4075
SMILES:
[H][C@]12C[C@@]1([H])c1c(C2)c(nn1-c1cnccn1)C(=O)N[C@H](CO)C(C)(C)C |r|
Structure:
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