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Target
Protein lin-28 homolog A
Ligand
BDBM50345476
Substrate
n/a
Meas. Tech.
ChEMBL_1734969 (CHEMBL4150505)
IC50
62500±n/a nM
Citation
 Lorenz, DA; Kaur, T; Kerk, SA; Gallagher, EE; Sandoval, J; Garner, AL Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7-Lin28 RNA-Protein Interaction. ACS Med Chem Lett 9:517-521 (2018) [PubMed]  Article 
Target
Name:
Protein lin-28 homolog A
Synonyms:
LN28A_MOUSE | Lin-28A | Lin28 | Lin28a | Protein lin-28 homolog A | Testis-expressed protein 17 | Tex17
Type:
PROTEIN
Mol. Mass.:
22729.80
Organism:
Mus musculus
Description:
ChEMBL_118142
Residue:
209
Sequence:
MGSVSNQQFAGGCAKAAEKAPEEAPPDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQGPSSQGKPAYFREEEEEIHSPALLPEAQN
  
Inhibitor
Name:
BDBM50345476
Synonyms:
CHEMBL4063466
Type:
Small organic molecule
Emp. Form.:
C22H22N4O6S2
Mol. Mass.:
502.563
SMILES:
CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(NC(C)=O)cc1
Structure:
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