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Target
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Ligand
BDBM50018055
Substrate
n/a
Meas. Tech.
ChEMBL_141590 (CHEMBL751748)
Ki
2200±n/a nM
Citation
 Dredar, SA; Blankenship, JW; Marchant, PE; Manneh, V; Fries, DS Design and synthesis of inhibitors of N8-acetylspermidine deacetylase. J Med Chem 32:984-9 (1989) [PubMed]  Article 
Target
Name:
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Synonyms:
Acetylpolyamine oxidase (APAO) | PAO | PAOX | PAOX_HUMAN | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Polyamine oxidase
Type:
Enzyme
Mol. Mass.:
70274.33
Organism:
Homo sapiens (Human)
Description:
Q6QHF9
Residue:
511
Sequence:
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL
  
Inhibitor
Name:
BDBM50018055
Synonyms:
7-Amino-heptan-2-one | CHEMBL176843
Type:
Small organic molecule
Emp. Form.:
C7H15NO
Mol. Mass.:
129.2001
SMILES:
CC(=O)CCCCCN
Structure:
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