Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50449581
Substrate
n/a
Meas. Tech.
ChEMBL_1740204 (CHEMBL4155954)
Ki
>10000±n/a nM
Citation
 Schoeder, CT; Kaleta, M; Mahardhika, AB; Olejarz-Maciej, A; ?a?ewska, D; Kie?-Kononowicz, K; Müller, CE Structure-activity relationships of imidazothiazinones and analogs as antagonists of the cannabinoid-activated orphan G protein-coupled receptor GPR18. Eur J Med Chem 155:381-397 (2018) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50449581
Synonyms:
CHEMBL4164171
Type:
Small organic molecule
Emp. Form.:
C27H32N2O3S
Mol. Mass.:
464.62
SMILES:
CCc1ccc(OCCCCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1 |t:21|
Structure:
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