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Target
Adenosine receptor A2b
Ligand
BDBM50449653
Substrate
n/a
Meas. Tech.
ChEMBL_1740324 (CHEMBL4156074)
IC50
91±n/a nM
Citation
 Varano, F; Catarzi, D; Vincenzi, F; Falsini, M; Pasquini, S; Borea, PA; Colotta, V; Varani, K Structure-activity relationship studies and pharmacological characterization of N Eur J Med Chem 155:552-561 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50449653
Synonyms:
CHEMBL4172715
Type:
Small organic molecule
Emp. Form.:
C15H13N5OS2
Mol. Mass.:
343.427
SMILES:
Cc1ccc(o1)-c1nc2c(N)nc(NCc3cccs3)nc2s1
Structure:
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