Reaction Details Report a problem with these data
Target
Beta-lactamase 1
Ligand
BDBM50450969
Substrate
n/a
Meas. Tech.
ChEMBL_1744439 (CHEMBL4178949)
Ki
0.800000±n/a nM
Citation
 González-Bello, C Antibiotic adjuvants - A strategy to unlock bacterial resistance to antibiotics. Bioorg Med Chem Lett 27:4221-4228 (2017) [PubMed]  Article 
Target
Name:
Beta-lactamase 1
Synonyms:
3.5.2.6 | BLA1_BACCE | Beta-lactamase | ampC | penPC
Type:
PROTEIN
Mol. Mass.:
33602.48
Organism:
Bacillus cereus
Description:
ChEMBL_117771
Residue:
306
Sequence:
MKNKKMLKIGMCVGILGLSITSLVTFTGGALQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRNILTEWMKGNATGDKLIRAGVPTDWVDADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSKDEKEATYDNQLIKEAAEVVIDAIK
  
Inhibitor
Name:
BDBM50450969
Synonyms:
CHEMBL4217629
Type:
Small organic molecule
Emp. Form.:
C8H9BN6O5S
Mol. Mass.:
312.07
SMILES:
OB(O)CNC(=O)S(=O)(=O)c1ccnc(c1)-c1nnn[nH]1
Structure:
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