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Target
Beta-2 adrenergic receptor
Ligand
BDBM50451638
Substrate
n/a
Meas. Tech.
ChEMBL_1746041 (CHEMBL4180551)
EC50
9000±n/a nM
Citation
 Kato, E; Kimura, S; Kawabata, J Ability of higenamine and related compounds to enhance glucose uptake in L6 cells. Bioorg Med Chem 25:6412-6416 (2017) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta
Type:
PROTEIN
Mol. Mass.:
46896.26
Organism:
Rattus norvegicus
Description:
ChEMBL_38603
Residue:
418
Sequence:
MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
  
Inhibitor
Name:
BDBM50451638
Synonyms:
CHEMBL4215907
Type:
Small organic molecule
Emp. Form.:
C22H27NO8
Mol. Mass.:
433.4517
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(C[C@H]3NCCc4cc(O)c(O)cc34)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Structure:
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