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Target
Chitooligosaccharidolytic beta-N-acetylglucosaminidase
Ligand
BDBM50452813
Substrate
n/a
Meas. Tech.
ChEMBL_1748392 (CHEMBL4182902)
Ki
>200000±n/a nM
Citation
 Chen, W; Shen, S; Dong, L; Zhang, J; Yang, Q Selective inhibition of ?-N-acetylhexosaminidases by thioglycosyl-naphthalimide hybrid molecules. Bioorg Med Chem 26:394-400 (2018) [PubMed]  Article 
Target
Name:
Chitooligosaccharidolytic beta-N-acetylglucosaminidase
Synonyms:
3.2.1.52 | Beta-hexosaminidase
Type:
PROTEIN
Mol. Mass.:
67953.88
Organism:
Ostrinia furnacalis
Description:
ChEMBL_117835
Residue:
594
Sequence:
MWSRRIPLFIFGVLVLILSVAAEDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTFHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERLVRMGIQAESLQPEWCYQNEGYCYS
  
Inhibitor
Name:
BDBM50452813
Synonyms:
CHEMBL4215095
Type:
Small organic molecule
Emp. Form.:
C25H29N3O8S
Mol. Mass.:
531.578
SMILES:
CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1SCC(=O)NCCCN1C(=O)c2cccc3cccc(C1=O)c23 |r|
Structure:
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