Reaction Details Report a problem with these data
Target
Ribonuclease P protein component
Ligand
BDBM50455344
Substrate
n/a
Meas. Tech.
ChEMBL_1754176 (CHEMBL4188936)
IC50
<50000±n/a nM
Citation
 Lounsbury, N; Eidem, T; Colquhoun, J; Mateo, G; Abou-Gharbia, M; Dunman, PM; Childers, WE Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin. Bioorg Med Chem Lett 28:1127-1131 (2018) [PubMed]  Article 
Target
Name:
Ribonuclease P protein component
Synonyms:
3.1.26.5 | Protein C5 | RNPA_STAAU | RNase P protein | RNaseP protein | Ribonuclease P protein component | rnpA
Type:
PROTEIN
Mol. Mass.:
13673.76
Organism:
Staphylococcus aureus
Description:
ChEMBL_117955
Residue:
117
Sequence:
MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
  
Inhibitor
Name:
BDBM50455344
Synonyms:
CHEMBL4204244
Type:
Small organic molecule
Emp. Form.:
C21H21FN4O3S
Mol. Mass.:
428.48
SMILES:
CC(C)c1ccc(OCC(=O)NNC(=S)NC(=O)c2cc3cc(F)ccc3[nH]2)cc1
Structure:
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