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Target
Uracil nucleotide/cysteinyl leukotriene receptor
Ligand
BDBM50458837
Substrate
n/a
Meas. Tech.
ChEMBL_1764838 (CHEMBL4200085)
EC50
115±n/a nM
Citation
 Baqi, Y; Pillaiyar, T; Abdelrahman, A; Kaufmann, O; Alshaibani, S; Rafehi, M; Ghasimi, S; Akkari, R; Ritter, K; Simon, K; Spinrath, A; Kostenis, E; Zhao, Q; Köse, M; Namasivayam, V; Müller, CE 3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17. J Med Chem 61:8136-8154 (2018) [PubMed]  Article 
Target
Name:
Uracil nucleotide/cysteinyl leukotriene receptor
Synonyms:
GPR17 | GPR17_HUMAN
Type:
PROTEIN
Mol. Mass.:
41013.71
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1353471
Residue:
367
Sequence:
MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL
  
Inhibitor
Name:
BDBM50458837
Synonyms:
CHEMBL4206497
Type:
Small organic molecule
Emp. Form.:
C18H23NO5
Mol. Mass.:
333.3789
SMILES:
CCCCCCOc1ccc2c(CCC(O)=O)c([nH]c2c1)C(O)=O
Structure:
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