Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50004575
Substrate
n/a
Meas. Tech.
ChEBML_29325
Ki
7.3±n/a nM
Citation
 Trivedi, BK; Bruns, RF [1,2,4]Triazolo[4,3-a]quinoxalin-4-amines: a new class of A1 receptor selective adenosine antagonists. J Med Chem 31:1011-4 (1988) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50004575
Synonyms:
CHEMBL268071 | Cyclopentyl-(1-trifluoromethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-amine
Type:
Small organic molecule
Emp. Form.:
C15H14F3N5
Mol. Mass.:
321.3004
SMILES:
FC(F)(F)c1nnc2c(NC3CCCC3)nc3ccccc3n12
Structure:
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